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Background: Inflammation plays a crucial role in the progression of coronary atherosclerosis
Background: Inflammation plays a crucial role in the progression of coronary atherosclerosis
Inflammation is thought to be a common precursor of atherosclerosis and diabetes
Methods: We consecutively enrolled 10,724 patients hospitalized for coronary heart disease undergoing PCI and followed up for major adverse cardiovascular and cerebrovascular events (MACCE), including all-cause mortality, cardiac mortality, non-fatal myocardial infarction, non-fatal Ischemic stroke and unplanned coronary revascularization
Results: 5298 patients (58.
Figure 1 Kaplan-Meier analysis of MACCE according to different FAR levels (A), glucose metabolism status (B), and FAR levels and glucose metabolism status (C)
Figure 1 Kaplan-Meier analysis of MACCE according to different FAR levels (A), glucose metabolism status (B), and FAR levels and glucose metabolism status (C)Table 1 Predictive values of FAR levels and different glucose metabolic states for the primary endpoint and each component in univariate and multivariate analyses
Table 1 Predictive values of FAR levels and different glucose metabolic states for the primary endpoint and each component in univariate and multivariate analysesFigure 2 Hazard ratios (95% CI) for MACCE in the four groups after adjustment for age, sex, body mass index, hypertension, previous myocardial infarction, previous PCI, previous stroke, eGFR, LVEF, LM/three-vessel disease, and SYNTAX score
Figure 2 Hazard ratios (95% CI) for MACCE in the four groups after adjustment for age, sex, body mass index, hypertension, previous myocardial infarction, previous PCI, previous stroke, eGFR, LVEF, LM/three-vessel disease, and SYNTAX scoreFigure 3 MACCE forest plots for different subgroups
Figure 3 MACCE forest plots for different subgroups
Conclusions: In this real cohort study, higher levels of FAR and DM were associated with poorer 5-year outcomes in patients with coronary artery disease undergoing PCI
Original source: Wang P, Yuan D, Zhang C, et al.
High fibrinogen-to-albumin ratio with type 2 diabetes mellitus is associated with poor prognosis in patients undergoing percutaneous coronary intervention: 5-year findings from a large cohort.
Cardiovasc Diabetol 2022 Mar 21;21(1)High fibrinogen-to-albumin ratio with type 2 diabetes mellitus is associated with poor prognosis in patients undergoing percutaneous coronary intervention: 5-year findings from a large cohort.
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