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Background: Dysglycemia or prediabetes is associated with cardiovascular risk, namely cardiovascular mortality
Dysglycemia or prediabetes is associated with cardiovascular risk, ie cardiovascular mortality
Thus, prediabetes is associated with T2D insulin resistance (IR), overweight and obesity, which are modifiable risk factors for other cardiometabolic risk factors, such as high blood pressure -- and greater susceptibility to cardiovascular disease
In cancer, however, strict interactions have been established between unhealthy diet and genetic susceptibility, but the impact of interactions between common genetic variants, Western diet, and life>
Methods: 1506 subjects were screened according to Findrisc score
Results: After HI, the miR-21/ROS/HNE axis was significantly decreased in patients with dysglycemia, and metabolic parameters such as insulin resistance, body mass index, microalbuminuria, reactive hyperemia index and skin fluorescence were improved
Figure 1 Expression of miR-21 in plasma after habitual intervention for 1 year
Figure 1 Expression of miR-21 in plasma after habitual intervention for 1 year
Table 1 Characteristics of subjects with low-miR-21
Table 1 Characteristics of subjects with low-miR-21Table 2 Characteristics of NR group
Table 2 Characteristics of NR groupFigure 2.
Figure 2.
HI affected epigenetic alterations associated with the miR-21 axis and confirmed the concept of reversibility of dysglycemia
Lower miR-21/ROS/HNE levels associate with lower glycemia after habit-intervention: DIPASON study 1-year later
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