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Background: Kidney transplantation is the preferred treatment option for patients with end-stage renal disease in terms of cost-effectiveness, improved quality of life, and reduced morbidity and mortality
Background: Kidney transplantation is the preferred treatment option for patients with end-stage renal disease in terms of cost-effectiveness, improved quality of life, and reduced morbidity and mortality
However, beta cells are sensitive to disturbances in cholesterol balance
Methods: This longitudinal cohort study included 480 RTRs without diabetes at baseline
RESULTS: The baseline residual cholesterol values for the RTR that subsequently developed into NODAT were significantly higher (0.
Figure 1 Kaplan–Meier analysis (log-rank test: p = 0.
Figure 1 Kaplan–Meier analysis (log-rank test: p = 0.
Table 1 Association of a 1 mmol/l increase in RLP cholesterol levels with NODAT events as determined by Cox regression analysis
Figure 2 Probability of NODAT occurrence according to residual lipoprotein cholesterol (RLP C) levels
Figure 2 Probability of NODAT occurrence according to residual lipoprotein cholesterol (RLP C) levels
Table 2 Logistic regression analysis of the Framingham diabetes risk score with and without the addition of RLP cholesterol
Conclusions: This study demonstrates that baseline RLP cholesterol levels are strongly associated with NODAT events, independent of several other recognized risk factors
Conclusions: This study demonstrates that baseline RLP cholesterol levels are strongly associated with NODAT events, independent of several other recognized risk factors
Original source: Szili-Torok T, Sokooti S, Osté MCJ, et al.
Remnant lipoprotein cholesterol is associated with incident new onset diabetes after transplantation (NODAT) in renal transplant recipients: results of the TransplantLines Biobank and cohort Studies .
Cardiovasc Diabetol 2022 Mar 16;21(1) Remnant lipoprotein cholesterol is associated with incident new onset diabetes after transplantation (NODAT) in renal transplant recipients: results of the TransplantLines Biobank and cohort Studies
