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Diabetes is an independent risk factor for heart and cerebrovascular diseases
.
Compared with non-diabetic people, the risk of heart and cerebrovascular diseases in diabetic patients is increased by 2 to 4 times
Blood sugar controls the development of cardiovascular complications
Background: Regular exercise is a widely recognized method for improving blood vessel function in patients with type 2 diabetes
.
However, the exercise intensity that produces the greatest benefit to the vascular structure and function of patients with type 2 diabetes remains unclear
Methods: 80 patients with type 2 diabetes were randomly divided into 3 groups: control group, HIIT combined RT group and MCT combined RT group
.
During the one-year intervention, exercise three times a week
Results: After adjusting the models of gender, baseline moderate-to-severe physical activity (MVPA) and mean arterial pressure (MAP) changes, the intention-to-treat analysis was used at the same time, the MCT group (β=-4.
25, P<0.
01) and the HIIT group (β= -3.
61, P<0.
01) Significant interactions were observed in carotid artery intima-media thickness (cIMT)
.
However, only HIIT observed peripheral arterial stiffness indicators from baseline to 1 year, such as cervical-radial pulse wave velocity (β=-0.
Only HIIT observes peripheral arterial stiffness indicators from baseline to 1 year, such as cervical-radial pulse wave velocity (β=-0.
Hemodynamics, arterial structure and function index for graph intent analysis
Note: β is a non-standardized coefficient adjusted according to gender, baseline MVPA and MAP changes, with 95% confidence interval DC: expansion coefficient; CD PWV: distal cervical pulse wave velocity; CF PWV: cervical-femoral pulse wave velocity; CR PWV cervical-radial pulse wave velocity; DBP: diastolic blood pressure
Note: β is a non-standardized coefficient adjusted according to gender, baseline MVPA and MAP changes, with 95% confidence interval DC: expansion coefficient; CD PWV: distal cervical pulse wave velocity; CF PWV: cervical-femoral pulse wave velocity; CR PWV cervical-radial pulse wave velocity; DBP: diastolic blood pressureHIIT: high-intensity interval training; IMT: intima-media thickness, MCT medium-intensity continuous training; SBP: systolic blood pressure; SI: stiffness index; VO 2 peak : peak oxygen uptake
HIIT: high-intensity interval training; IMT: intima-media thickness, MCT medium-intensity continuous training; SBP: systolic blood pressure; SI: stiffness index; VO 2 peak : peak oxygen uptake 2 peak*Significant difference between groups, P<0.
*Significant difference between groups, P<0.
Both the MCT group and the HIIT group reduced cIMT, while only the HIIT group improved the peripheral arterial stiffness index and expansion coefficient
Therefore, we believe that HIIT may be a meaningful way to improve the vascular complications of type 2 diabetes
HIIT may be a meaningful way to improve the vascular complications of type 2 diabetes
Original source:
Magalhães JP, Melo X, Correia IR, et al.
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