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On August 5, 2020, Professor Zhang Chenyu of Nanjing University, Zhang Lei of Wuhan Virus, and Yi Yongxiang of Nanjing Second Hospital published a paper in Cell Discovery Magazine, which confirmed through clinical trials that RNAmi in the gold and silver soup can be effectively absorbed by the human body by drinking and effectively inhibited in the body the replication of the new coronavirus, accelerating the transvulsion of new crown patients, indicating that the treatment of gold and silver cobras may greatly help cure new patients and prevent the cobback.
MicroRNA (miRNA) is a class of endogenous small RNAs with a length of approximately 20-24 nucleotides that have a variety of important regulatory roles within cells.
miRNA is highly conservative across different species, and in recent years studies have suggested that miRNA can regulate gene expression across species.
2012, Professor Zhang Chenyu published a research paper in the Journal of Cell Research entitled: Exogenous plant MIR168a specifically targets the mamlian LDLRAP1: evidence of cross-kingdom regulation by microRNA.
the study is the first to find that extragenous plant miRNAs in food regulate the expression of targeted genes in mammals.
Professor Zhang's team found that miRNA can be stable in serum and plasma in humans and animals.
recent studies have shown that microbubbles (Mvs) from human plasma are a mixture of particles, exosomes, and other vesicle structures, and that many types of MV in human plasma contain miRNA. further research
showed that miRNAs were selectively encased in MV and actively delivered to receptor cells, and that external miRNA regulates target gene expression and receptor cell function.
humans and animals have exogenous plant miRNAs in serum and plasma, and more than half of the plant miRNAs detected in serum and plasma are present in MV.
further in vitro and in vivo analysis confirmed for the first time that the food-sourced exogenous plant MIR168a can regulate the expression of the mouse LDLRAP1 protein across species through the gastrointestinal pathways of mice and into various organs, especially in the liver.
miRNAs in gold and silver flowers can suppress the virus in 2015, Professor Zhang Chenyu's team published a research paper in Cell Research magazine entitled Honeysuckle-encoded atypical microRNA2911 directly targets influenza a viruses.
the study found that MIR2911 in gold and silver flowers can be absorbed by mice and directly targeted at the virus, thereby inhibiting virus replication.
mir2911 can be stable in gold and silver flower soup, after oral absorption into the cycle, and delivered to various organizations.
, after feeding the mice 0.5 ml of gold and silver flower soup, the average cell in the mouse lung tissue contained 1600 MIR2911 molecules, which had full biological function.
mir2911, which enters the lung epiderm cells, binds directly to the mRNA of various influenza viruses, directly inhibiting the replication of the virus.
miR2911 can inhibit multiple virusES MIR2911 in 94% of the virus genomes have binding sites, followed by cell level or animal level experiments also proved that MIR2911 in the Ebola virus, Zika virus, African swine plague virus, Middle Eastern respiratory fever virus and swine rotavirus virus and other virus genomes have binding sites, can inhibit the replication of these viruses.
miR2911 inhibits the bioinformatics of the new coronavirus, and the team predicted that there were 179 MIR2911 binding sites in the SARS-CoV-2 genome.
the team then identified 28 binding points using fluoroprotein enzymatics, which were widely distributed in the genome of the new corona virus, suggesting that MIR2911 may inhibit the translation of almost all SARS-CoV-2 proteins.
inosome experiments showed that the exosome MIR2911 with a concentration of 13.2 pM inhibited 93% viral replication (reduced from 4.09 x 10E9 to 2.87 x 10E8 copy/ml), indicating that the absorbed MIR2911 directly and fully inhibited SARS-CoV-2 virus replication.
, the team evaluated the inhibition of SARS-CoV-2 replication by drinking the gold and silver flower soup.
the results showed that after the patient drank the gold and silver flower soup, the human exosome MIR2911 increased significantly, and the level of the virus in the body decreased significantly.
these results show that MIR2911 can be fully absorbed by drinking the gold and silver flower soup, and the absorption of MIR2911 significantly blocks the replication of SARS-CoV-2 virus.
more important, patients who drank the daily broth were significantly faster than the control group.
MIR2911 is able to stabilize the presence of gin and silver flower soup, and directly inhibit virus replication in the human body after oral administration, and accelerate the patient's transpose, the treatment of the gin flower soup may greatly help cure the new crown patient and prevent the COVID-19 pandemic.
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