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    Home > Active Ingredient News > Digestive System Information > CELL: How to regulate intestinal microbes through diet to improve immunity?

    CELL: How to regulate intestinal microbes through diet to improve immunity?

    • Last Update: 2021-07-30
    • Source: Internet
    • Author: User
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    Existing studies have shown that the intestinal microbiota is very important to human health, and we need to strengthen our understanding of the factors that affect the composition and function of this microbial community
    .
    And diet has become a driving factor in the composition and function of the microbiota


    .


    In prospective dietary intervention studies, short-term changes in diet have also been shown to rapidly change the human gut microbiota
    .

    The joint study of gut microbiota and human biology shows that manipulating gut microbes may be a powerful means to change many aspects of human health
    .
    Diets that target the gut microbiota can strengthen, introduce or eliminate specific functions or taxa, and have proven to be a powerful way to achieve precision medicine


    .


    Precise

    At present, a key question is whether there are broad, non-personalized dietary recommendations that can take advantage of the interaction between the existing microbiota and the host to improve the health of different groups of people
    .
    For example, non-communicable chronic diseases (NCCD) are largely driven by chronic inflammation, and with the development of industrialization, the incidence is rapidly increasing


    .


    Diet can regulate the gut microbiota, which in turn can affect the immune system
    .
    Recently, researchers have determined how two dietary interventions that target the microbiota, namely plant fiber and fermented food, affect the microbiota and immune system of healthy adults


    .


    Diet can regulate the gut microbiota, which in turn can affect the immune system Diet can regulate the gut microbiota, which in turn can affect the immune system immunity

    Diet regulates the immune system

    Diet Regulates the Immune System Diet Regulates the Immune System

    Researchers through a 17-week randomized, prospective study (n = 18/arm), combined with microbiome and host omics measurements, including extensive immune analysis, found specific effects of diet
    .
    Among them, the high-fiber diet increased the carbohydrate-degrading carbohydrate activity enzyme (CAZymes) coded by the microbiome , and at the same time, the diversity of the microbial community remained stable


    .


    High-fiber diet increases the sugar-degrading carbohydrate active enzymes coded by the microbiome High-fiber diet increases the sugar-degrading carbohydrate active enzymes coded by the microbiome

    In addition, a high-fermented food diet steadily increases the diversity of the microbiota and reduces inflammation markers
    .

    High-fermented food diet steadily increases the diversity of microbiota and reduces inflammation markers High-fermented food diet steadily increases the diversity of microbiota and reduces inflammation markers

    These data emphasize the combination of dietary interventions with in-depth and longitudinal immunization and microbiome analysis, which can provide personalized and population-wide insights
    .
    In addition, fermented foods may be valuable in combating the reduction in microbiota diversity and the increase in inflammation that are prevalent in industrialized societies


    .


    Fermented foods may be valuable in combating the reduction in microbiota diversity and increased inflammation that are ubiquitous in industrialized societies.


    Original source:

    Original source:

    Hannah C.


    Hannah C.


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