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In the past decade, the contribution of different nutrients to the biosynthesis, bioenergy and antioxidant requirements of cancer cells has been extensively studied
In many of these studies, researchers have found that cancer cells can get what they need based on mutations and metabolic preferences driven by the microenvironment
The existing research results on the above issues are contradictory.
So far, there have been fewer strategies aimed at supplementing specific nutrients rather than restricting diet
Existing studies on a cohort of more than 1,000 colorectal cancer patients have shown that greater intake of marine n-3 PUFAs after diagnosis is associated with lower cancer-related deaths and longer disease-free survival
Rich in n-3 and n-6 polyunsaturated fatty acids can promote iron death-mediated anti-cancer effectsRich in n-3 and n-6 polyunsaturated fatty acids can promote iron death-mediated anti-cancer effect Rich in n-3 and n-6 polyunsaturated fatty acids can promote iron death-mediated anti-cancer effect
The results showed that in the acidic environment of tumors, n-3 and n-6 polyunsaturated fatty acids (PUFA) selectively induced iron death of cancer cells
n-3 and n-6 polyunsaturated fatty acids (PUFA) selectively induce iron death of cancer cells n-3 and n-6 polyunsaturated fatty acids (PUFA) selectively induce iron death of cancer cells
In addition, compared with a diet rich in monounsaturated fatty acids, a diet rich in n-3 long-chain PUFA significantly slowed the growth of tumors in mice , and this effect was further enhanced after taking DGATi or ferroproteinase inducers
A diet rich in n-3 long-chain PUFA significantly delayed the growth of mouse tumors.
Original source:Original source:
Emeline Diergeet al.
Emeline Dierge et al.
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