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According to reports, maternal obesity is related to neurodevelopmental disorders in offspring.
This study aims to explore the mechanism link between maternal obesity and cognitive behavior deficits of offspring, and the beneficial effects of dietary fiber on behavior deficits of offspring.
child
Compared with normal-weight mothers, the proportion of overweight and obese children in overweight and obese mothers increased significantly (p<0.
Compared with normal-weight mothers, the proportion of overweight and obese children in overweight and obese mothers increased significantly (p<0.
In order to study the effect of maternal obesity on the neurodevelopment of offspring, the study established an animal model: female C57BL/6J mice were fed control diet (mCD) or high-fat diet (mHFD) for 12 weeks.
In addition, studies have shown that obesity in mother mice disrupts the behavior and gut microbiota of offspring.
Maternal obesity disrupts the behavior and gut microbiota of the offspring.
The cognitive and social dysfunctions associated with maternal obesity are caused by changes in the intestinal microflora of the offspring.
Liu Xiaoning,Li Xiang,Xia Bing et al.
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