Cell Metabolism: Big Discoveries! Eating for a fixed period of time can help you lose weight.

In recent years, Interstitial fasting has become increasingly popular because of its ability to cause significant clinical weight loss and prevent metabolic diseases.
is a general name for three different forms of diet: fasting every other day, a 5:2 diet, and limited-time eating (Time-Restricted Feeding, TRF).
despite the growing popularity of limited-time eating, so far there have been no clinical trials to assess whether dietary rules like these have a clinical weight loss effect.
September 1, 2020, the Krista A. Varady team at the University of Illinois at Chicago published a research paper online in Cell Metabolism entitled "Effectsof 4- and 6-h Time-Restricted Feeding on Weight and Cardiometabolic Health: A Randomized Controlled Trials in Adults with Obesity", the first clinical trial to assess the clinical effects of time-limited eating.
study found that four- and six-hour limited-time eating can cause a slight weight loss within eight weeks and is expected to be an intervention for weight loss.
these diets can also improve certain aspects of heart metabolic health.
recent years, interstitial fasting has become increasingly popular because of its ability to cause significant clinical weight loss and prevent metabolic diseases.
is a general name for three different forms of diet: fasting every other day, a 5:2 diet, and limited-time eating (Time-Restricted Feeding, TRF).
the next day fasting includes a "fasting day" on which energy intake is severely restricted (e.g. 0-800 kcal / 0-3,350 kJ of daily energy consumption), alternating with a day of casual eating.
5:2 diet is a modified version of the next-day fasting, which includes fasting days of only two days a week, followed by five days of casual eating days.
the previous two, limited-time eating has clear limits on the duration of the meal, which requires that the eating must be done over a certain period of time.
drink 0 calories outside the limited-time eating window.
people don't need to count calories and food intake during the feeding period.
4-hour and 6-hour eating time windows are the two most popular time-limited eating modes.
despite the growing popularity of limited-time eating, so far there have been no clinical trials to assess whether dietary rules like these have a clinical weight loss effect.
in the study, researchers screened 24 obese adult volunteers with a body mass index (BMI) of 30-50kg/m2 who did not meet the test criteria and randomly divided the remaining 58 into three different groups, 19 of whom were given four-hour limited-time eating (4-h TRF) trials Twenty people were tested for six hours of limited-time eating (6-h TRF) and 19 as control groups.
a variety of interfering factors were eliminated from the trial, the number of groups in the final four-hour time-limited eating trial was 16, the number of groups in the six-hour time-limited eating trial was 19, and the number of control groups was 14.
in this study, the volunteers were first expected to have a baseline weight stabilization period of 2 weeks, followed by 8 weeks of dry expectations.
During the intervention period, the 4-hour time limit eating time window was 3 to 7 p.m. and the 6-hour limited-time eating time window was 1 to 7 p.m., and there were no restrictions on the control group's diet patterns and lifestyle.
The trial group was able to eat without calories, regardless of food type or intake, while the fasting time window was able to consume only enough water and 0 energy drinks such as tea, coffee and soda.
researchers tracked the weight, blood pressure, lipids, insulin resistance, inflammatory cytokines, oxidative stress, LDL cholesterol, HDL cholesterol, triglycerides and other physiological indicators of the volunteers.
8-week trial results showed significant weight loss in the 4-hour and 6-hour time-limited eating intervention group compared to the control group, about 3% weight loss in both laboratory groups, and some improvement in insulin resistance and oxidative stress.
energy intake of the two trial groups was reduced by about 550 kca per day, and this study showed no significant difference between a four-hour time limit and a six-hour time limit.
Compared to the control group, neither of the two limited-time eating patterns had serious side effects, with moderate side effects such as dizziness, nausea, headache, and diarrhea peaking in the second week of dry expectations and disappearing in the third week of dry expectations until the end of the trial.
the U.S.-China problem of a small number of experimental groups, and the effect of food intake in the eating window on weight loss effects needs to be further studied.
.