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On June 24, Beijing time, "Cell" published an online publication titled "Genome design of hybrid potato" by Huang Sanwen's team from Shenzhen Institute of Agricultural Genomes, Chinese Academy of Agricultural Sciences (Lingnan Modern Agricultural Science and Technology Guangdong Laboratory Shenzhen Branch) (Genome Design of Hybrid Potatoes)" research results
In order to solve the problems of long breeding cycle and high cost of potato block reproduction faced by the potato industry, Huang Sanwen's research team and Yunnan Normal University and other domestic and foreign superior units launched the "Excellent Potato Project", using the theory and method of "genome design" to cultivate For hybrid potatoes, replace quadruple sports seeds with double sports seeds, and use hybrid seed propagation instead of potato block propagation
On the basis of overcoming self-incompatibility and analyzing the genetic mechanism of self-incompatibility in the early stage, Huang Sanwen’s team used genomic big data to make breeding decisions and established a hybrid potato genome design and breeding process, including four links: (1) Use For the selection of the starting material for breeding inbred lines, the selection criteria are the low heterozygosity of the genome of the starting material and the small number of harmful mutations; (2) The genetic analysis of the selfed population of the starting material is mainly based on the whole genome Partial segregation analysis and phenotypic evaluation to determine the distribution of large-effect harmful alleles and superior alleles in the genome; (3) Breeding of inbred lines, selection of large-effect harmful mutations, superior aggregation, etc.
Using this strategy, the team has developed the first generation of highly homozygous (>99%) inbred lines and hybrid lines "Youshu No.
The successful selection and breeding of "Youshu No.
Huang Sanwen is the corresponding author of the paper, and Zhang Chunzhi is the first author.
Link to the paper: https://doi.