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The new coronavirus can be detected in the lungs and multiple extrapulmonary organs of patients with severe coronary pneumonia
.
According to the patient's organ tropism and pathological characteristics, new coronary pneumonia can be divided into viral intrapulmonary subtypes and systemic subtypes
Recently, Academician Bian Xiuwu, Associate Professor Ping Yifang of the Army Military Medical University, and Professor Zhang Shuyang of Peking Union Medical College Hospital, as co-corresponding authors, published a research paper entitled: A cohort autopsy study defines COVID-19 systemic pathogenesis in Cell Research .
Cell Research A cohort autopsy study defines COVID-19 systemic pathogenesisThe study described the systemic pathological characteristics of SARS-CoV-2 infection, and provided new enlightenment for the development of new coronary pneumonia treatment and the recognition of infection mechanisms
.
The presence and tissue damage of permanent SARS-CoV-2 in the lungs and extrapulmonary organs indicate that direct virus invasion is the pathogenic mechanism of critically ill patients with new coronary disease
.
SARS-CoV-2 may hijack monocytes, macrophages, and vascular endothelial cells at physiological barriers, serving as a portal for systemic transmission
The median age of the 26 autopsy cases used in the study was 67.
5 years.
The presence of permanent viruses and tissue damage in the lungs and extrapulmonary organs indicate that the direct invasion of the new coronavirus is the main pathogenic factor in critically ill patients.
This study describes the systemic pathological characteristics of the new coronavirus infection and provides a reference for the development of new coronary pneumonia treatment and the understanding of the mechanism of infection
Original source:
Original source:Yao, XH.
A cohort autopsy study defines COVID-19 systemic pathogenesis.
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