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    Home > Biochemistry News > Biotechnology News > "Cell" Yeast Nuclear Pore Complex Model

    "Cell" Yeast Nuclear Pore Complex Model

    • Last Update: 2022-01-07
    • Source: Internet
    • Author: User
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    Boston University researchers have developed a yeast nuclear pore complex model

    The research results provide an in-depth perspective for studying the communication between the nucleus and the cell body

    Nuclear pore complexes (NPCs) are a large number of multi-protein complexes that serve as channels for molecules to enter and exit the nucleus


    Researchers at Boston University School of Medicine (BUSM) used rapid freezing, electron microscopy, and calculation methods to build a comprehensive model of yeast NPCs, revealing the interconnected structure of their core scaffolds


    One is easier to study in isolated samples to provide a radially dense form in live yeast cells;

    A more detailed overview of the second extended form, although this "in situ" form is currently visualized at a lower level of detail


    Corresponding author Dr.


    According to the researchers, the model will better understand how these large passages are combined and how they adapt to changes in traffic by expanding the central passage


    Researchers believe that these findings now lay the foundation for studying how viruses use this important way to infect cells and change their physiology to cause disease


    These findings were published online in the journal Cell




    Magazine

    "Cell"

    DOI

    10.


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