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Interpersonal relationships need to be maintained by effective communication, as is the human microenvironment.
Recently, a research team led by the University of Sydney Research in Australia has identified a communication pathway to control cell growth and survival, which may provide new ideas for the development of treatments for diseases such as cancer and diabetes
Cellular communication refers to the transmission of information from one cell to another cell to produce a corresponding response through the medium
Obviously, human cells communicate mainly through the first method
As we all know, insulin as an effective growth signal, its secretion will increase after the human body eats, and promote the production of blood sugar in muscle and fat cells
PI3K/AKT signal pathway
Because the PI3K/AKT signaling pathway is closely related to insulin resistance, it is essential for the survival of eukaryotic cells
In order to solve this problem, researchers began to find a mechanism to control the stable conduction of this signal
Mechanism model of terminal insulin signaling
This mechanism is centered on the main component "Akt" of the phosphoinositide 3-kinase (PI3K) signaling pathway, acting as a "failure safety" to avoid signal instability, similar to a heater or a thermostat in an oven.
Negative feedback regulation depends on Akt
Note: The original text has been deleted
Reference materials:
[1]https://elifesciences.
[2]https://medicalxpress.