Cells: The acute stage of neocyto pneumonia has a greater T-cell effect than antibodies

BEIJING, Sept. 17 (Xinhua Zhang Jiaxin) 16, the United States "Cell" magazine published the latest paper of the La Jolla Institute of Immunology, said that in the acute stage of infection with coronary pneumonia, T-cell-mediated immune response plays an important role in the control of the virus and reduce the severity of the disease. In addition, patients over the age of 65 who have a weak or un coordinated immune response will face worse prognostics.
findings suggest that the new crown candidate vaccine should be committed to effectively stimulating immune responses, including antibodies, auxiliary T-cells and killer T-cells, to ensure protective immunity in the body.
the study, scientists collected blood samples from 50 patients with neo-coronary pneumonia and analyzed how the three branches of the adaptive immune system - antibodies, auxiliary T-cells and killer T-cells - played a role in the patients.
studies have found that immune responses to antibodies, auxiliary T-cells and killer T-cells can be detected in all fully recovered patients, while adaptive immune responses vary widely in patients with acute neocyctic pneumonia, and neutral antibodies, auxiliary T-cells, or killer T-cells lack one or more.
that antibodies do not appear to play an important role in controlling acute neo-coronary pneumonia. In contrast, T-cells are particularly associated with protective immune responses.
"When we looked at these 111 measurement parameters, we found that, in general, the broader and more coordinated a patient's adaptive response, the better the recovery." In particular, the strong T-cell response specific to the new coronavirus is a precursor to a less serious disease," said study co-lead author Dr. Rowling Modbach. "
may also explain why people over the age of 65 are more susceptible to the disease," said Dr. Shane Crotty, one of the authors of the paper. T-cell responses in these populations are worse and the immune response is less coordinated, which can lead to more severe or fatal cases of neocyto pneumonia. The researchers believe that the high susceptibleness of older people to neocyto pneumonia may be due to their smaller T-cells. These cells are T cells that have not yet met the conditions for "fighting" the virus. As people get older, the number of T-cells that can be deployed in the immune system decreases and the number of cells that can be activated to respond to new viruses decreases. The body's adaptive immune response can also be delayed or weakened.