CGH: In patients with intestinal polyps, after the removal of large serrated polyps, the clip closure does not reduce the risk of bleeding

A sessile serrated adenoma is a colorectal adenoma/polyp that resembles a hyperplastic polyp but has unique histological features
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Under the endoscope, the appearance is flat and sessile, soft and smooth, the surface is pale, the boundary is unclear, and the surface is usually covered with mucus

A sessile serrated adenoma is a colorectal adenoma/polyp that resembles a hyperplastic polyp but has unique histological features

 

This trial is a multicenter trial in which researchers randomly divided patients with large sessile polyps (≥20 mm) who underwent endoscopic mucosal resection (EMR) into a group with or without basal clipping
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The analysis was stratified by the histological subtype of the study polyp, classified as serrated [sessile serrated lesion (SSL) or hyperplastic polyp (HP)] or adenomatous polyp, and then compared the clip group and the control group in The difference in severe postoperative bleeding occurred within 30 days after colonoscopy

 

A total of 179 participants with 199 LSPs (191 SSL and 8 HP) and 730 participants with 771 adenomatous polyps were included in this study
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Overall, 5 LSP patients (2.

This study demonstrated a lower risk of bleeding after removal LSP by EMR, and in this group the prevention of occlusion removal of the substrate is no significant advantage
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This study shows that the benefits of endoscopic clipping after EMR may have better specificity for adenomatous polyps> 2 cm located in the proximal colon

This study demonstrated a lower risk of bleeding after removal LSP by EMR, and in this group the prevention of occlusion removal of the substrate is no significant advantage

Seth D.

Clip closure does not reduce risk of bleeding after resection of large serrated polyps: results from a randomized trial.
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