Chemokine Receptors and Neural Stem Cells
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Last Update: 2020-12-28
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Source: Internet
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Author: User
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Neural stem cells (NSCs) represent a limited population of progenitor cells in the central nervous system that sustain theirself-renewal and multipotency from early development to adulthood. Recent evidence suggests that chemokine receptors are constitutivelyexpressed by NSCs and are directly involved in stem cell biology. As cell surface receptors, chemokine receptors also providean important avenue to enrich these cells and further identify the potential molecular pathways required to maintain theirbiological functions. Here, I describe in vitro methods that have been widely applied to sort, culture, maintain, and differentiateNSCs.
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