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    Home > Medical News > Latest Medical News > Chen Wei team: New coronavirus antibody research has made a major breakthrough!

    Chen Wei team: New coronavirus antibody research has made a major breakthrough!

    • Last Update: 2020-11-27
    • Source: Internet
    • Author: User
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    At 22:00 BST on June 22nd, the international top academic journal Science published important results online, and Chen Wei, a member of the Chinese Academy of Engineering and a researcher at the Institute of Military Medicine of the Academy of Military Sciences, discovered the first highly effective medium- and monoclonal antibodies targeting the N-side domain of the hedgehog protein. This is another world-class scientific research achievement after Chen Wei's team developed the adenovirus vector recombination new crown vaccine, which was the first in the world to enter Phase II clinical trials.
    Currently, the new crown pneumonia epidemic is raging around the world, the development of effective vaccines and antibodies is a major challenge for scientists in various countries, vaccines for healthy population prevention, and antibodies for patients' special effects treatment, the combination of the two can be prevented and treated. Since the outbreak of new crown pneumonia, Chen Wei academician first went to Wuhan, led the team around the pathogen transmission variation, rapid detection technology, vaccine antibody development and other emergency scientific research, and achieved a series of important scientific research results.antibodies are a class of protective antibodies that the body should produce against primary stimuli. At present, the world's scientific research teams for the new coronavirus drug design and machinery research, are focused on the new coronavirus prick protein binding domain, and our team is by identifying the prick protein N-side domain of the efficient neutral monoclonal antibody, found that the N-side domain is the new coronavirus prickline protein new fragile table, which provides a new scientific pathway for therapeutic antibodies and other drug design.
    Chen Wei's team, in collaboration with Zhou Qiang of West Lake University, used cryoscopic technology to analyze the interaction interface between antibodies and prickly proteins with high precision, providing key information for clarifying their antiviral mechanisms. When used alone, the antibody can play a high level of viral medianation and can also be used as an efficient "cocktail" therapy in conjunction with antibodies targeting the binding domain of the subject. This provides a strong candidate for the treatment of neo-coronary pneumonia, as well as a new idea for drug and surface vaccine design and mechanism of action of new coronavirus targeting the N-side domain of hedgehog protein. (Chief CCTV reporter Zhang Zhenwei, Yan Longfei, Zhuang Yingna, Li Chao, Zhang Zhanyu)
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