China has stopped using freon drugs since 2016, affecting 750 million people

Source: Cypress blue sorting 2016-07-12 according to the Southern Metropolis Daily, China will not apply for the use exemption of medical Freon since 2016, and will start to phase out the medical inhalers using freon ingredients From this year, China will completely stop using freon in the field of medicine, but the substance is widely used in atomized drugs "If the domestic drug research and development using alternative ingredients fails to keep up with the overall discontinuation, it means that a large number of patients with COPD and asthma in China need to rely on imported drugs," said Zhong Nanshan, academician of the Chinese Academy of engineering and director of the State Key Laboratory of Guangzhou Institute of respiratory diseases It is reported that China signed relevant international agreements in 1991, promising to gradually reduce the production and use of ozone depleting substances such as Freon In order to meet the clinical medication needs of patients with asthma and chronic obstructive pulmonary disease in China, China has started the application for exemption of Freon for medical inhalation aerosol since 2009, with the exemption period from 2010 to 2015 Since 2016, China will no longer apply for exemption from the use of medical freon, and begin to phase out the use of pharmaceutical inhalers with Freon ingredients "At present, there are two main types of chronic airway diseases in the world, one is chronic obstructive pulmonary disease, with about 400 million patients, the other is asthma, with 350 million patients," Zhong said Inhaled aerosol is an important way to treat this kind of chronic respiratory diseases, so aerosol can not be replaced, but Freon needs to be replaced by other products If the 400 million plus 350 million people use aerosols every day, the environmental pollution is unimaginable " At present, a large number of Freon inhaled aerosols are used in our country, and there are few domestic non Freon aerosols Therefore, it is of great significance to promote the independent research and development and production of non Freon inhalation aerosol in China "If we implement this elimination system, but our country does not have (alternative aerosol), it will always depend on imports, so we have to produce by ourselves." Zhong Nanshan said that if China realizes the self-produced non Freon medicine inhalation aerosol, its cost will be at least one third lower than the current Freon aerosol, and much lower than the imported drugs After the news came out, some medical people soon cheered Isn't that to say that the sales volume of related alternative varieties will rise? Since fluorine-containing drugs for the treatment of COPD and asthma were stopped in 2016, which drugs will be stopped and which drugs will face the opportunity of market expansion? The following is the relevant information queried from the open channels and the database of the State Food and Drug Administration: in 2014, the pharmaceutical manufacturers exempted CFCs for pharmaceutical inhaled aerosols, and some of the non fluoride alternative product manufacturers, salmeterol and fluticasone powder inhalers (Seretide) Glenn Suskbynederformotero (Xin Bi Ke Bao), AstraZeneca Tiotropium Bromide Spray (Si Lihua), Berlin, Yin Ge Han tiotropium inhalation powder mist Nanchang Hongyi pharmaceutical tiotropium inhalation powder mist Tiotropium bromide powder mist (Tianqing Suolu) Zhengda Tianqing beclomethasone propionate powder mist agent Shanghai Xinyi beclomethasone propionate nasal mist agent Shandong Jingwei Beclomethasone propionate suspension for inhalation