echemi logo
  • Product
  • Supplier
  • Inquiry
    Home > Biochemistry News > Biotechnology News > China's first independent research and development of human-derived anti-CD25 monoclonal antibody issued the first prescription

    China's first independent research and development of human-derived anti-CD25 monoclonal antibody issued the first prescription

    • Last Update: 2020-06-17
    • Source: Internet
    • Author: User
    Search more information of high quality chemicals, good prices and reliable suppliers, visit
    Kidney transplantation, as the most ideal kidney replacement therapy for patients with end-stage chronic renal failure, is rapidly being promoted worldwideChina's kidney transplant ational scientific registration system data center statistics show that in 2015, China completed a total of 7131 kidney transplants, after the United States ranked second in the worldHowever, the long-term survival rate of transplants after kidney transplantation has been lowAccording to the latest OPTN/SRTR annual report published in February 2019 in Am J Transplant, the 10-year total-cause transplant failure rate is 49.7%, meaning only 50.3% of the 10-year transplant survival ratethe application of immunosuppressants is very important in order to improve the long-term survival rate of the graftClinical applications have shown that antibody-induced therapy can reduce acute rejection and reduce the incidence of acute rejection in early postoperative times by 30%-40%In recent years, the choice of reasonable immunosuppressant program to reduce the incidence of adverse reactions and improve the long-term survival of kidney transplant patients has become a new trend, and humanized antibodies with fewer heterogeneous proteins are the needs of organ transplantation development in ChinaJune 2019, the first humanized anti-CD25 monoclonal antibody Kennito, independently developed by Sansheng Guojian, obtained the drug GMP certificate from the State Drug Administration to prevent acute rejection reactions caused by kidney transplantation, which can be combined with conventional immunosuppressive programs, significantly improve the survival rate of transplanted organs and improve the quality of patient sexistNote: Cut in the original text
    This article is an English version of an article which is originally in the Chinese language on and is provided for information purposes only. This website makes no representation or warranty of any kind, either expressed or implied, as to the accuracy, completeness ownership or reliability of the article or any translations thereof. If you have any concerns or complaints relating to the article, please send an email, providing a detailed description of the concern or complaint, to A staff member will contact you within 5 working days. Once verified, infringing content will be removed immediately.

    Contact Us

    The source of this page with content of products and services is from Internet, which doesn't represent ECHEMI's opinion. If you have any queries, please write to It will be replied within 5 days.

    Moreover, if you find any instances of plagiarism from the page, please send email to with relevant evidence.