China's synthetic new compounds can kill Helicobacter pylori

According to Professor Bi Hongkai of Nanjing Medical University's School of Basic Medicine, humans are the only natural host of Helicobacter pylori, which is not easily killed by stomach acidAntibiotics are commonly used clinically to combat Helicobacter pylori, but long-term use can lead to resistance to strains, disrupt the balance of gastrointestinal flora, and produce a range of side effects"Our idea is to develop new antimicrobials to reduce antibiotic useBi Hongkai said that the team synthesized a small molecular compound of zinc linolenic acid, the current compound through in vitro antiseptic effect, gastric mucosa tissue pathological repair, inflammatory factor regulation, cell and organ damage evaluation and other studies, found that it can selectively kill Helicobacter pylori, not easy to produce resistance, high safety, with research and development potentialthe new compound has been patented by the state, the results of the antimicrobial field of the authoritative journal "antibacterial preparations and chemotherapy" published recently.