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Recently, the research team of the Institute of Microbiology of the Chinese Academy of Sciences has made the fermentation level of L-homoserine exceed 84 grams per liter and the conversion rate reached 50% through systematic metabolic engineering transformation and fermentation process improvement, which has good economic efficiency.
The research team established a fermentation pathway with an overall balance of reducing power through pathway coupling design, and reused the carbon dioxide released in the reducing power supply pathway.
L-homoserine is a naturally occurring non-protein amino acid, which can be used as a pharmaceutical intermediate and has a good market prospect