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The incidence of gestational diabetes mellitus (GDM) in mainland China was 14.
The incidence of gestational diabetes mellitus (GDM) in mainland China was 14.
Studies have found that high homocysteine levels (hyperhomocysteinemia, hHcy) are risk factors for GDM, and dietary patterns affect serum homocysteine (Hcy) levels; for example, a Mediterranean diet can significantly reduce serum Hcy level
There are three types of dietary pattern extraction methods, using different methods depending on the purpose of the study
There are three types of dietary pattern extraction methods, using different methods depending on the purpose of the study
Therefore, this study aimed to extract hHcy-related dietary patterns using the RRR method and analyze its relationship with the incidence of GDM to explore the possible role of dietary patterns in Hcy levels and GDM
A total of 512 pregnant women at 24-28 weeks who underwent routine obstetric examinations in our hospital from January 2019 to December 2020 were included in this study
A total of 512 pregnant women at 24-28 weeks who underwent routine obstetric examinations in our hospital from January 2019 to December 2020 were included in this study
Three dietary patterns were identified in this study ( Table 2)
Compared with the lowest quartile of Mode 1, subjects in the highest quartile had higher energy intake, higher serum Hcy, higher serum FA and B12, all linearly trend
Logistic regression analysis showed that after adjustment for multiple confounding factors,the score of mode 2 was significantly positively correlated with the incidence of GDM ( P< 0.
Logistic regression analysis showed that after adjustment for multiple confounding factors, the score of mode 2 was significantly positively correlated with the incidence of GDM ( P< 0.
Taken together, hHcy-related dietary pattern scores were significantly positively associated with GDM risk, suggesting that dietary patterns can be adjusted to increase the intake of foods rich in one-carbon unit metabolism-related vitamins, thereby affecting Hcy levels and may contribute to the development of GDM.
Taken together, hHcy-related dietary pattern scores were significantly positively associated with GDM risk, suggesting that dietary patterns can be adjusted to increase the intake of foods rich in one-carbon unit metabolism-related vitamins, thereby affecting Hcy levels and may contribute to the development of GDM.
Original source:
Original source:Liu YH, Lu LP, Yi MH, et al.
Liu YH, Lu LP, Yi MH, et al.
Study on the correlation between homocysteine-related dietary patterns and gestational diabetes mellitus: a reduced-rank regression analysis study.
BMC Pregnancy Childbirth .
2022;22(1):306.
Published 2022 Apr 10.
doi:10.
1186/s12884-022-04656-5.
BMC Pregnancy Childbirth
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