Funded by the National Natural Science Foundation of China (Grant No.
Chronic migraine is a type of neurological disease with recurrent hemispheric, throbbing headaches as the main symptoms.
As early as the Eastern Han Dynasty, Zhang Zhongjing's "Treatise on Febrile Diseases and Miscellaneous Diseases" had a record of "retching, spitting up saliva, headache, and Wuzhuyu Decoction".
The above research results suggest that the Jingfang Wuzhuyu Decoction in the treatment of chronic migraine can promote the synthesis of intestinal neurotransmitters, thereby affecting the release of CGRP in the trigeminal nerve and reducing pain sensitization.
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