Chinese scholars have found nanoantibodies resistant to the new crown all-human source

it is learned that Fudan University School of Basic Medicine Professor Should Tianlei and other researchers found a series of anti-new crown all-human nanoantibodies, for the development of new coronavirus drugs and treatment programs of great significance.The results are reported to have been published in the latest issue of the journal Cell Hosts and Microbes.The new coronavirus has infected millions of people worldwide, and there are no specific drugs available, so there is an urgent need to develop safe and effective antiviral antibodies. According to Professor Tianlei, the whole human source refers to the antibody gene all derived from human beings.In recent years, a new class of antibodies known as "nanoantibodies" has been favored by the pharmaceutical industry because of their small molecular weight, low production costs and stable properties. However, nanoantibodies originate from camels or alpacas, even after humanization still contains certain camel-derived ingredients, making its human use a safety hazard.In order to solve the problem of safety hazards, the research team and partners developed a new technology and took the lead in designing all-human nanoantibodies with natural embryo gene. High affinity, with low cost, fast production, easy to purify, etc. , is the characteristics of this kind of all-human nanoantibodies.Due to its small size and excellent physiculative properties, this class of all-human nanoantibodies can be developed as atomized inhalation agents, which quickly transport a large number of antibodies to lesions such as altruism. In theory, it is particularly suitable for the treatment of respiratory diseases such as neo-crown pneumonia, Mr. Should said.Using this new technology, the team successfully screened dozens of all-human nanoantibodies in the binding area of the new coronavirus, two of which were powerful all-human nanoantibodies of the new coronavirus, and were able to target the special hidden ideosphere of the virus S protein. (China News Network)