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Chinese scholars have made progress in the research of site-selective amination

 Last Update: 2022-08-20
 Source: Internet
 Author: User

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Under the support of the National Natural Science Foundation of China (Grant No.

Alkyl allylamine backbones are widely present in drug molecules

The team used a cobalt oxime catalyst for the hydrogen extraction reaction (HAT) to realize the site-selective transfer of double bonds, which solved the difficult problem of site selectivity control; the reaction released hydrogen at the same time, avoiding the pre-activation of the substrate in the synthesis of allylamine.

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