Chinese scientists have developed an mRNA vaccine that can be effectively protected in one dose
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Last Update: 2021-02-10
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Source: Internet
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Author: User
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February 6, Science and Technology Daily reporter from Shanxi Institute of Advanced Innovation was informed that the Institute and
Institute of Microbiology Yan Jinghua, Gao Fu and China CDC Tan Wenjie developed mRNA vaccine, a dose can be effectively protected. There is no need for the current two-dose vaccination programme.
results were published in the February 3, 2021 issue of TheNature Communications, a sub-issue. Entitled: A single-dose mRNA vaccine provides a long-term protection for hACE2 transgenic from from SARS-CoV-2.
, the team developed a nucleoside-modified mRNA vaccine wrapped in lipid nanoparticles (LNP), which encodes the new coronavirus S protein RBD domain (mRNA-RBD).
test results show that the single dose of the mRNA vaccine developed by Chinese scientists can cause strong antibody and cellular immune response, and provide near-complete protection for hACE2 genetically modified mice against wild new coronavirus infection. Further studies have shown that the mRNA vaccine induces high levels of meso-antibodies that last at least 6.5 months. These data suggest that the mRNA vaccine provides long-term protection against the new coronavirus in hACE2 genetically modified mice with a single dose.
since there is still no effective treatment for neo-crown pneumonia, vaccination is the most effective measure to prevent and stop the new crown pandemic.
The nucleoside-modified mRNA vaccine, developed by the research team, is enough to induce a strong antibody and cellular immune response with a single dose, providing near-complete long-term protection against wild neo-coronavirus infections in hACE2 genetically modified mice.
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