Chinese scientists have successfully mapped the high-resolution three-dimensional genome of corn

Xinhua News Agency, Wuhan, June 16 (Reporter Li Wei) The research team of Huahua Agricultural University recently successfully mapped the high-resolution three-dimensional genome in which corn active expression genes participate, identified the three-dimensional interoperability model of genomic shunned regulatory elements, and revealed the potential mechanism of corn 3D genome structure regulation gene expression and influence esoteric variation. The results show that the study of high-resolution three-dimensional genome of corn is of great significance to the study of the functional genome of corn and the study of the complex agro-artistic features of corn.
reporter learned from Huazhong Agricultural University on the 16th, the university Professor Li Sheng, Professor Yan Jianbing and Professor Li Guoliang team cooperation of this research results, recently published online in the international academic journal Nature Newsletter.
more than 80 percent of the sequences in the corn genome are located in the intergene region, which contains many genetic variants that have been identified that affect important agro-shapes, but the mechanisms by which these shun regulatory elements located in the intergenerational region affect gene expression are unclear.
three-dimensional genome is the "key key" to crack the genetic mechanism, it is particularly important to analyze the mechanism of the smooth regulation element in corn by means of three-dimensional genome. The traditional three-dimensional structure research method is limited by the low precision and other factors, it is difficult to obtain high-resolution three-dimensional structure map, restricting scientists to crack this mechanism.
The research team from the Chinese Academy of Agricultural Sciences, the Academy of Plant Sciences and the School of Information has worked together across the field to produce relevant data using innovative experimental methods to successfully construct a three-dimensional genome structure map of high-resolution corn with precision to the genetic level.
based on a high-resolution map, the team further detailed the basic characteristics of the promoter and promoter interaction genes, while the researchers suggested that the proximity of three-dimensional space provided the basis for gene expression regulation.