Chinese scientists reveal key processes for early development of embryos in primates

From a developmental biology perspective, the most important moment in a person's life is not birth, marriage and death, but the movement of the intestinesThis is the most special stage of early embryonic development, with cells increasing directly from hundreds to thousands, tens of thousandsAbnormalities often lead to major diseases such as pregnancy failure or postnatal organ defectsthe study, carried out in collaboration with the Institute of Zoology of the Chinese Academy of Sciences, Kunming Institute of Zoology, and the Institute of Innovation in Stem Cells and Regenerative Medicine, established a new in vitro culture system that can support the in vitro growth of crab-eating monkey embryos for up to 20 days after fertilizationIn vitro cultured embryos fully reflect the key events of early development in the body after implantation, and the development reaches the stage of the formation of the primary embryoWang Hongmei, one of the authors of thenewsletter and a researcher at the Institute of Animals of the Chinese Academy of Sciences, said that the fertilized eggs of mammals form a blastocyst, and before and after the bed in the womb, some cells in the embryo begin to move, rearrange and differentiate, start the movement of the original intestine, form the internal, middle and outer three embryo layers, and lay the foundation for the establishment of the embryo body axis and organ developmentDue to ethical limitations, in vitro human embryo culture can not exceed 14 days after fertilization, and primate intestinal movement occurred 14 days after fertilization, so biologists know little about the human progenitor movement, a milestone in the development of primates.