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    Home > Biochemistry News > Biotechnology News > Church and Academician Jin Li of Fudan University officially launched the China Personal Genome Project

    Church and Academician Jin Li of Fudan University officially launched the China Personal Genome Project

    • Last Update: 2020-08-21
    • Source: Internet
    • Author: User
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    On October 29th George Church, a geneticist and pioneer of gene editing technology, was hired as an emeritus professor at Fudan University.
    , Church joined forces with Fellow Jin Li of Fudan University to officially launch the China Personal Genome Project.
    63-year-old Church with silver hair and a Santa-like silver beard, like Darwin, the biologist who wrote The Origin of Species.
    's research career is also decrypting life and creation: he was a participant in the first generation of gene sequencing research, the main establisher of the second generation of gene sequencing methods, which laid the foundation for subsequent gene sequencing and editing studies.
    he is also an advocate and organizer of the Global Genome Project, currently a professor at Harvard University and the Massachusetts Institute of Technology, and a fellow of the American Academy of Sciences, the Academy of Engineering, the Academy of Arts and Sciences.
    Church told the News of the Year that his life has been devoted to a range of different genetic sequencing methods, as well as a series of different methods of gene editing.
    these sequencing and editing methods are progressing slowly.
    some editing methods are moving slower than the "gene-cut" CRISPR, but they perform better in some areas, which is where further research is needed. The main problem with
    gene editing is the need to break the double-stranded DNA (double helix), risking damage to normal tissue.
    , but there are other ways in which the toor DNA and recepor DNA can be directly bonded without breaking the double helix.
    genes have important effects on human life characteristics, but the human genome is often flawed, missing, repetitive, and structurally incorrect, leading to disease.
    role of genome sequencing and editing is to screen out problematic genes and save the next generation from genetic disorders by rewriting them.
    but the problems of inaccuracies and information interpretation of gene sequencing, and the problems of gene editing off-target remain to be solved.
    The genetic research in which Church is involved is also imaginative: reversing aging through gene therapy; editing pig genes so that the endogenous retrovirus (PERVs) in pigs does not activate in the human body, removing barriers to transplanting pig organs in humans; writing books on DNA and preserving them permanently; and extracting extinct mammoth DNA to modify Asian elephant genes to save them from extinction.
    Chuchi launched the Personal Genome Project in the United States in 2005, hoping to recruit 100,000 individuals from around the world and share their genetic data to answer the question of why humans suffer from all kinds of diseases, or not. The key to
    this goal is the integration and sharing of data, a common human treasure.
    invited participants from the public to share their genome data, and more than 5,000 people have so far expressed their participation.
    China is the first country in Asia to launch a personal genome program.
    countries that have started the project include the United States, Canada, the United Kingdom and Austria.
    , led by Professor Jin Li, will begin collecting samples in December from the China Personal Genome Project, which is run by Fudan University's dedict group research institute.
    .
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