Cinnamic acid

Cinnamic acid

Cinnamic acid

[Synonyms] cinnamic acid, trans-Cirnamic acid

【Structural formula】

[Molecular formula and molecular weight] C ₉ H ₈ O ₂ ; 148.
16

[Source] The dry bark of Lauraceae Cinnamomum cassia Presl
.

【Properties】White powder
.

This product is soluble in methanol
.

Melting point: 132～133℃
.

【Purity Check】

TLC

1.
Thin layer plate silica gel G

Developing solvent hexane - ether - acetic acid (5: 5: 0.
1)

Check under UV lamp (254nm)

2.
Thin layer plate silica gel G

Eluent petroleum ether - cyclohexane - ethyl - carboxylic acid (10:30:15:1)

Check under UV lamp (254nm)

High performance liquid chromatography

Chromatographic column AgilentC ₁₈ , 5um (4.
6mm×250mm)

The mobile phase methanol -0.
1% acetic acid (50:50), 1.
0ml / min

Detection wavelength 285nm

【Structural identification】273,216,205
.

2596, 1684, 1631, 1450, 1344, 1288, 1227, 933, 766
.

EI-MS m/z: 148[M] ⁺ , 131, 103, 91, 77, 51
.

¹ H-NMR (CD ₃ OD) δ: 6.
50 (1H, d, J=16Hz, H-8), 7.
39～7.
42 (3H, m, H-2,4,6), 7.
57～7.
60 (2H, m , H-3, 5), 7.
70 (1H, d, J=16Hz, H-7)
.

¹³ C-NMR (CD ₃ OD) δ: 170.
3 (C-9), 119.
3 (C-8), 146.
3 (C-7), 135.
8 (C-1), 129.
1 (C-2, 6), 129.
9 ( C-3, 5), 131.
3(C-4)
.

【Storage】Dry and airtight
.

Related Links: Swertia Picrinoside