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Myocarditis has been considered a rare complication after COVID-19 mRNA vaccination, especially in young adults and adolescent men
.
Recently, the heart blood vessels published a research article in the authoritative magazine on the field of Circulation, according to the US Centers for Disease Control (CDC) in 12-39 year-olds, per one million vaccinated mRNA vaccine, myocarditis / pericarditis incidence About 12.
6 cases
.
In the reported cases, patients with myocarditis presented with chest pain, usually within 2-3 days after the second dose of mRNA vaccination, and accompanied by elevated cardiac troponin levels
.
Most electrocardiogram abnormalities with ST-segment elevation, cardiac MRI of all tested patients revealed myocarditis, and there was no evidence of acute COVID-19 or other viral infections
Infect
In the study, a patient with cardiomyopathy genotype was negative, but the level of autoantibodies against certain autoantigens increased, and the number of natural killer cells increased
.
Although the mechanism of myocarditis is not yet clear, it is speculated that the molecular simulation between the spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and autoantigens triggers the previously existing and dysregulated diseases in some patients.
Immune diagnosis
The research data shows that although there are few cases of myocarditis, the benefits of COVID-19 mRNA vaccination-risk assessment tends to be favorable for all age groups and gender groups; therefore, it is recommended that people 12 years and older are vaccinated with COVID-19 Vaccine
.
.
Original source:
Original source:Biykem Bozkurt,et al.
