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    Home > Active Ingredient News > Endocrine System > Clin Chem: The relationship between the plasma phospholipid fatty acid profile during pregnancy and the diagnosis and treatment of gestational diabetes

    Clin Chem: The relationship between the plasma phospholipid fatty acid profile during pregnancy and the diagnosis and treatment of gestational diabetes

    • Last Update: 2021-10-20
    • Source: Internet
    • Author: User
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    Background: Plasma phospholipid fatty acids (FAs) in the first and second trimester of pregnancy have a prospective relationship with the risk of gestational diabetes (GDM)
    .


    However, the changes in fatty acids after the diagnosis and treatment of gestational diabetes and their effects on glucose metabolism and control have not been fully studied


    Plasma phospholipid fatty acids (FAs) in the first and second trimesters of pregnancy have a prospective relationship with the risk of gestational diabetes (GDM)


    child

    Results: Compared with women without gestational diabetes, 8 fatty acids in gestational diabetes patients had a significant doubling of the baseline value (23-31 weeks)
    .


    The folding changes of 5 fatty acids are reduced [Myristic acid (14:0): B: 0.


    Figure 1 The mean and multiple changes of plasma phospholipid FAs and FA-derived indicators in patients with gestational diabetes and the control group at the second visit
    .

    Figure 1 The mean and multiple changes of plasma phospholipid FAs and FA-derived indicators in patients with gestational diabetes and the control group at the second visit
    .


    Figure 2 The multiples of changes in plasma phospholipid FAs and FA-derived indicators according to GDM status during two visits
    .

    Figure 2 The multiples of changes in plasma phospholipid FAs and FA-derived indicators according to GDM status during two visits
    .


    Conclusion: Our study identified 8 fatty acids that have a unique pattern of changes before and after the diagnosis of gestational diabetes, and there are significant differences between women with and without gestational diabetes
    .


    Our findings may help clarify the role of FA metabolism in the pathophysiology, disease management and progression of gestational diabetes


    Our study identified 8 fatty acids, which have a unique pattern of changes before and after the diagnosis of gestational diabetes, and there are significant differences between women with and without gestational diabetes


    Li L, Zhu Y, Wu J,et al.


    Changes of Plasma Phospholipid Fatty Acids Profiles in Pregnancy in Relation to the Diagnosis and Treatment of Gestational Diabetes Mellitus in this message
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