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Studies have shown that there is an association between dietary intake of advanced glycation end products (AGEs) and children's allergic outcomes
.
Recently, a research article was published in Clinical and Experimental Allergy, an authoritative journal in the field of allergic diseases.
Researchers assessed the mother’s AGEs intake and the offspring’s occurrence of asthma, wheezing, atopic dermatitis, allergic rhinitis and food allergy.
And try to clarify whether the intake of AGEs is related to umbilical cord serum cytokines/chemokines
.
The Healthy Start study recruited pregnant women over 16 years old, a prospective prenatal cohort from Colorado (N=1410)
.
The researchers analyzed detailed information including 962 on dietary adequacy (≥2 recall surveys) and allergy outcomes
diagnosis
The median [IQR] AGEs intake for the entire sample was 11919kU/day [8293-16573]
.
An unadjusted analysis showed that maternal AGEs intake during pregnancy was positively correlated with rhinitis under 8 years old (HR=1.
The study showed that maternal intake of AGEs has nothing to do with asthma and allergy outcomes in offspring
.
The effects of exposure to AGEs during pregnancy on the development of children may be different from those of postpartum exposure
The maternal intake of AGEs has nothing to do with the outcome of asthma and allergies in the offspring
Original source:
Carina Venter.
Advanced glycation end product intake during pregnancy and offspring allergy outcomes: A Prospective cohort study in this message
