Clin Gastroenterology H: A low-fat, high-fiber diet can reduce intestinal inflammation in patients with ulcerative colitis

In the United States, the incidence of ulcerative colitis (UC) is increasing year by year
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The current treatment plan relies on safe but expensive mesalazine and immunosuppressive therapies, but this may lead to an increased risk of body infections and hematological malignancies

 In the United States, the incidence of ulcerative colitis (UC) is increasing year by year

 

This study included a total of 17 UC patients in remission or mild disease activity from February 25, 2015 to September 11, 2018 for a parallel group crossover study
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Participants were randomly assigned to 2 groups and received an LFD diet (10% of calories from fat) or iSAD diet (35%-40% of calories from fat) during the first 4 weeks, followed by a 2-week washout period.

 

During the entire study period, all patients maintained UC in remission
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Compared with baseline, both iSAD and LFD improved the quality of life of patients.

Figure: The impact of different dietary patterns in UC patients on inflammation

This study confirmed that either LFD or iSAD diet can improve the quality of life of UC patients
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However, the LFD diet can reduce inflammatory markers and the degree of intestinal disorders in stool samples

This study confirmed that either LFD or iSAD diet can improve the quality of life of UC patients

 

Original source:

Julia Fritsch.

Low-Fat, High-Fiber Diet Reduces Markers of Inflammation and Dysbiosis and Improves Quality of Life in Patients With Ulcerative Colitis.

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