Clin Gastroenterology H: Association of Physical Activity with Risk of Liver Fibrosis, Sarcopenia, and Cardiovascular Disease in NAFLD Patients

Although effective treatment strategies for NAFLD remain unclear, life>management of NAFLD
.

Several recent studies have reported that moderate to vigorous physical activity is associated with a lower risk of death in patients with nonalcoholic fatty liver disease

Although effective treatment strategies for NAFLD remain unclear, life>management of NAFLD

 

In this multicenter, retrospective study, researchers recruited a total of 11,690 individuals who underwent a health screening program and were assessed for physical activity (metabolic equivalent task [MET]-min/week) between 2014 and 2020.
NAFLD subjects
.

Liver fibrosis in patients was assessed using the fibrosis-4 index, NAFLD fibrosis score, and FibroScan-AST score

screening

 

RESULTS: The prevalence of fibrosis, sarcopenia, high probability of ASCVD, and high CAC scores decreased significantly with increased physical activity (P<0.
001)
.

In the fully adjusted model, physical activity exceeding 600 MET-min/week (≥ 3rd quartile) was independently associated with a reduced risk of fibrosis ([aOR]=0.

Figure: The relationship between physical activity and liver fibrosis

This study found that physical activity is protective against fibrosis, sarcopenia, and CVD in NAFLD, and the authors also observed a dose-response relationship, with greater physical activity being significantly associated with fibrosis, sarcopenia, and CVD.
negative correlation
.

This study found that physical activity is protective against fibrosis, sarcopenia, and CVD in NAFLD, and the authors also observed a dose-response relationship, with greater physical activity being significantly associated with fibrosis, sarcopenia, and CVD.
negative correlation
.

 

 

Original source:

Ho Soo Chun.

Association of physical activity with risk of liver fibrosis, sarcopenia, and cardiovascular disease in NAFLD.
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