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    Home > Active Ingredient News > Digestive System Information > Clin Gastroenterology H: Comparison of the efficacy of carbapenem antibiotics and third-generation cephalosporins in the treatment of spontaneous bacterial peritonitis

    Clin Gastroenterology H: Comparison of the efficacy of carbapenem antibiotics and third-generation cephalosporins in the treatment of spontaneous bacterial peritonitis

    • Last Update: 2021-05-08
    • Source: Internet
    • Author: User
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    Spontaneous bacterial peritonitis (SBP) is a bacterial ascites infection that often occurs in patients with liver cirrhosis and ascites.


    Spontaneous bacterial peritonitis (SBP) is a bacterial ascites infection that often occurs in patients with liver cirrhosis and ascites.


     

    Researchers retrospectively collected 865 patients who were treated at 7 medical centers in South Korea between September 2013 and January 2018 who had SBP for the first time (275 of which were positive for bacterial culture; 103 were TGC-resistant bacterial infections) .


     

    The results of the study showed that among patients who initially received empiric antibiotic therapy, 95 (11.


    Figure: The therapeutic effect of different antibiotics on spontaneous bacterial peritonitis

    This study confirmed that for patients who showed SBP for the first time, empirical treatment with carbapenems could not reduce hospital mortality compared with TGCs treatment.


    This study confirmed that for patients who showed SBP for the first time, empirical treatment with carbapenems could not reduce hospital mortality compared with TGCs treatment.


     

    Original source:

    Sun Woong Kim.


    Empirical Treatment With Carbapenem vs Third-generation Cephalosporin for Treatment of Spontaneous Bacterial Peritonitis.
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