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Clin Gastroenterology H: Efficacy and safety analysis of 5-HT-4 receptor agonist Misapride in the treatment of patients with irritable bowel syndrome

 Last Update: 2021-03-18
 Source: Internet
 Author: User

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Irritable bowel syndrome (IBS) refers to recurrent or persistent abdominal pain and abnormal bowel habits related to the functional gastrointestinal tract.

The researchers included 171 patients with IBS-C defined by Rome III who attended 33 medical centers in Japan from December 2012 to August 2013.

The results of the study showed that at week 4, the improvement in the weekly frequency of CSBMs in all Misapride groups from baseline was greater than that in the placebo group (P = .

This study found that through a prospective study of Japanese people, Misapride can increase the stool frequency of IBS-C patients, reduce the abdomen, and improve the overall IBS-C symptoms, and it is well tolerated.

Original source:

Shin Fukudo.

Efficacy and Safety of 5-HT4 Receptor Agonist Minesapride for Irritable Bowel Syndrome with Constipation in a Randomized Controlled Trial.
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