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The fecal bacteria transplantation is to transplant the functional bacteriota in the feces of healthy donors into the patient's intestines in a certain way, to reconstruct the stability of the intestinal microorganisms, and to regulate the imbalance of the intestinal bacteriota, thus playing the role of treating the disorders of the intestinal bacteriota.
current studies suggest that fecal cytos transplantation (FMT) be used to treat patients with refragtic Thyroid infection (CDI), FMT can cure nearly 80% of patients with severe or outbreakal CDI (SFCDI).
study has been carried out in this study.
researchers collected characteristic and clinical data on 430 people with severe Thyrobacter difficile infection (SFCDI) at a medical center between January 2009 and December 2016.
subgroup analysis was carried out in 199 patients with outbreak CDI and 110 patients with refrheditable SFCDI.
all patients were treated with anti-CDI antibiotics for 5 days or more.
the prevalence of CDI-related mortality and colonectomy was lower after the implementation of the FMT program.
, the CDI-related mortality rate was 10.2% prior to the implementation of the FMT program, compared with 4.4% after the implementation of the FMT program .02.
for patients with outbreak CDI, the CDI-related mortality rate was 21.3% prior to the implementation of the FMT program, compared with 9.1% after the implementation of the FMT program .015.
for patients with refrative SFCDI, the CDI-related mortality rate was 43.2% prior to the FMT programme, compared with 12.1% after the FMT programme (P .lt;.001).
FMT treatment significantly reduced CDI-related colonectomy in SFCDI patients (before 6.8% vs. 2.7%; P s .041), outbreak CDI patients (before 15.7% vs 5.5%; P s.017).
, the FMT program significantly reduced CDI-related mortality in incurable SFCDI inpatients.
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