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Gate venous thrombosis (PVT) refers to blood clots that appear in the main vein and the inner branch of the liver, and non-malignant venous thrombosis in patients with cirrhosis is more frequent than in patients with non-hepatic cirrhosis.
because PVT patients are usually asymptomatic and rarely have abdominal discomfort, it usually takes a long time to diagnose PVT.
most PVT patients are slow and have no clinical symptoms.
, however, some patients, especially those with acute PVT, may experience abdominal discomfort or complications of hypertension in the veins.
, PVT is reported to be associated with liver compensation disorders and may affect mortality.
incidence of non-malignant PVT in patients with cirrhosis ranged from 0.6% to 23%.
few studies have explored the prevalence of PVD in patients with acute disproparentic cirrhosis.
In addition, the relationship between acute insexual cirrhosis and PVT remains unclear, so this study aims to investigate the prevalence and clinical significance of PVT in patients with non-malignant cirrhosis and acute loss of liver function (AD).
researchers conducted a retrospective study of patients with acute exacerbation of chronic liver disease between January 2015 and December 2016 (n - 2,600 patients) and also collected similar patients from July 2018 to January 2019 (n - 1370 patients).
also analyzed data on PVT prevalence, clinical performance and risk factors from 2,826 patients with cirrhosis without AD.
results showed that the prevalence of PVT was 9.36% in patients with cirrhosis and AD, significantly higher than that in patients without AD cirrhosis at 5.24% (P- .04).
in patients with cirrhosis and AD, 63.37 percent recently developed PVT.
patients with PVT had significantly higher rates of varicose rupture bleeding than patients without PVT (47.33% VS 19.63% ;P.001 vs. In this study, the proportion of PVT in patients with AD was significantly higher than in patients without AD.
PVT is associated with increased varicose bleeding, which also increases the risk of AD.
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