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Plasma odd-chain saturated fatty acids (OCFA) are negatively correlated with the risk of type 2 diabetes (T2D) , and can also be used as a biomarker of dairy fat intake
Plasma odd chain saturated fatty acids (the OCFA) and type 2 diabetes (of T2D) was negatively correlated with the risk of plasma odd chain saturated fatty acids (the OCFA) and type 2 diabetes (of T2D) was negatively correlated with the risk of diabetes
This study aims to explore the prospective association between OCFA-containing lipids and the risk of T2D, as well as their dietary determinants
In the European Prospective Survey on Cancer and Nutrition-Potsdam Study (n=27548), researchers used a nested case cohort design (sub-cohort: n=1248; T2D cases: n=820; median follow-up 6.
cholesterol
The total concentration of lipids containing OCFA and the proportion of each lipid
The total concentration of lipids containing OCFA and the proportion of each lipidResearchers have observed that the heterogeneous integration of OCFA in different lipids: triacylglycerol, FFA, CE, and phosphatidylcholine contribute the most to the plasma abundance of OCFA
Heterogeneous integration of OCFA in different lipids: triacylglycerol, FFA, CE and phosphatidylcholine contribute the most to the plasma abundance of OCFA.
In women, several phospholipids containing OCFA are negatively correlated with T2D risk.
Correlation between C15:0 and C17:0 lipids and total fat intake at baseline
Correlation between C15:0 and C17:0 lipids and total fat intake at baselineIn addition, CE (C17:0), monoacylglycerol (C15:0) and diacylglycerol (C15:0) are negatively correlated with T2D risk; FFA (C17:0) is positively correlated with female T2D risk
CE (C17:0), monoacylglycerol (C15:0) and diacylglycerol (C15:0) are negatively correlated with T2D risk; FFA (C17:0) is positively correlated with female T2D risk CE (C17:0), Monoacylglycerol (C15:0) and diacylglycerol (C15:0) are negatively correlated with T2D risk; FFA (C17:0) is positively correlated with female T2D risk
In summary, lipids containing OCFA are related to the risk of T2D in a lipid- and gender-specific manner; in addition, their levels in the body are also related to the intake of a variety of foods
Lipids containing OCFA are related to the risk of T2D in a lipid- and gender-specific manner; in addition, their levels in the body are also related to the intake of a variety of foods
Original source:
Prada Marcela,Wittenbecher Clemens,Eichelmann Fabian et al.
Association of the odd-chain fatty acid content in lipid groups with type 2 diabetes risk: A targeted analysis of lipidomics data in the EPIC-Potsdam cohor
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