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    Home > Active Ingredient News > Endocrine System > Clin Nutr: The relationship between the content of odd-chain fatty acids in lipids and the risk of type 2 diabetes

    Clin Nutr: The relationship between the content of odd-chain fatty acids in lipids and the risk of type 2 diabetes

    • Last Update: 2021-08-14
    • Source: Internet
    • Author: User
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    Plasma odd-chain saturated fatty acids (OCFA) are negatively correlated with the risk of type 2 diabetes (T2D) , and can also be used as a biomarker of dairy fat intake


    Plasma odd chain saturated fatty acids (the OCFA) and type 2 diabetes (of T2D) was negatively correlated with the risk of plasma odd chain saturated fatty acids (the OCFA) and type 2 diabetes (of T2D) was negatively correlated with the risk of diabetes

    This study aims to explore the prospective association between OCFA-containing lipids and the risk of T2D, as well as their dietary determinants


    In the European Prospective Survey on Cancer and Nutrition-Potsdam Study (n=27548), researchers used a nested case cohort design (sub-cohort: n=1248; T2D cases: n=820; median follow-up 6.


    cholesterol

    The total concentration of lipids containing OCFA and the proportion of each lipid

    The total concentration of lipids containing OCFA and the proportion of each lipid

    Researchers have observed that the heterogeneous integration of OCFA in different lipids: triacylglycerol, FFA, CE, and phosphatidylcholine contribute the most to the plasma abundance of OCFA


    Heterogeneous integration of OCFA in different lipids: triacylglycerol, FFA, CE and phosphatidylcholine contribute the most to the plasma abundance of OCFA.


    In women, several phospholipids containing OCFA are negatively correlated with T2D risk.


    Correlation between C15:0 and C17:0 lipids and total fat intake at baseline

    Correlation between C15:0 and C17:0 lipids and total fat intake at baseline

    In addition, CE (C17:0), monoacylglycerol (C15:0) and diacylglycerol (C15:0) are negatively correlated with T2D risk; FFA (C17:0) is positively correlated with female T2D risk


    CE (C17:0), monoacylglycerol (C15:0) and diacylglycerol (C15:0) are negatively correlated with T2D risk; FFA (C17:0) is positively correlated with female T2D risk CE (C17:0), Monoacylglycerol (C15:0) and diacylglycerol (C15:0) are negatively correlated with T2D risk; FFA (C17:0) is positively correlated with female T2D risk

    In summary, lipids containing OCFA are related to the risk of T2D in a lipid- and gender-specific manner; in addition, their levels in the body are also related to the intake of a variety of foods


    Lipids containing OCFA are related to the risk of T2D in a lipid- and gender-specific manner; in addition, their levels in the body are also related to the intake of a variety of foods


    Original source:

    Prada Marcela,Wittenbecher Clemens,Eichelmann Fabian et al.


    Association of the odd-chain fatty acid content in lipid groups with type 2 diabetes risk: A targeted analysis of lipidomics data in the EPIC-Potsdam cohor

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