Clin Nutrition: Oral lactic acid slows gastric emptying and suppresses appetite in men

Lactic acid is a key metabolite in the body's intermediate metabolism and serves as an alternative energy source for major organs including the heart and brain
.

To complete this study, the researchers conducted a related test on ten healthy male volunteers on two separate occasions: 1) after oral ingestion of D/L-sodium lactate and 2) after oral ingestion of isotonic equal volume of NaCl Appetite was assessed by questionnaires and an ad libitum meal test at the end of each study day after intravenous injection of isolactate D/L-sodium lactate
.

Results of the study showed that plasma concentrations of growth differential factor 15 (GDF15) were significantly increased after oral and intravenous lactate administration (p < 0.
001), with no detectable statistical difference between interventions (p = 0.
15)
.

Image: Lactic acid slows gastric emptying

This study demonstrates that oral lactate has a direct effect on the upper gastrointestinal tract
.

Original source:

Mette Glavind Bülow Pedersen.