Clin Nutrition: Thresholds for visceral fat area and body fat percentage to define sarcopenic obesity and its clinical consequences in Chinese cancer patients

Obesity is a major public health problem because it increases the risk of medical illness and premature death
.

Global obesity rates have nearly tripled since 1975, and according to the World Health Organization, 39% of adults worldwide were overweight [body mass index (BMI) ≥ 25 kg/m ² ] in 2016, and 13% of adults were Obesity (BMI ≥ 30 kg/m ² )

Obesity is a major public health problem because it increases the risk of medical illness and premature death

 

Sarcopenic obesity (SOB) was originally used to describe the coexistence of sarcopenia and obesity
.

The core mechanism of SOB involves fat deposition and a pro-inflammatory cascade, and crosstalk with biologically active muscle tissue results in a negative feedback loop that promotes a progressive increase in fat mass and loss of lean body mass and muscle strength

 

 

The researchers conducted a prospective study of 2480 cancer patients
.

Clinical materials, bioelectrical impedance analysis measurements, and follow-up data were analyzed

Quality of Life Statistics

 

Results: The cut-off points for visceral fat area that best classified patients according to time of death were >75.
6 cm ² in men and > 61.
2 cm ²
in women .

The cut-off point for body fat percentage is 15% for men and 25% for women

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Figure: Correlation between SOB and mortality

 

According to sex-specific cutoffs, SOB is strongly associated with adverse clinical outcomes and mortality in cancer patients
.

These results demonstrate the importance of SOB detection in routine clinical practice for improving patient assessment, cancer prognosis, and intervention

According to sex-specific cutoffs, SOB is strongly associated with adverse clinical outcomes and mortality in cancer patients

 

Original source:

WeiJi.

Thresholds of visceral fat area and percent of body fat to define sarcopenic obesity and its clinical consequences in Chinese cancer patients.
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