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Chronic constipation (CC) is a common functional gastrointestinal disease with a global prevalence rate of 2% to 27%.
CC prevalence increased with age, and individuals with CC generally showed significantly lower quality of life physically and mentally.
, the decline in detobation desire (DD) is very noticeable, and DD is a feeling that arises when the rectal wall expands and is an important part of normal detobation.
often report loss of detocest desire (LODD) due to damage to rectal sensations.
therefore, the purpose of this study was to assess (i) the prevalence of LODD in individuals with and without CC, and (ii) the satisfaction with the prevalence of LODD in individuals with CC and its associated treatment.
The main study was an Internet survey conducted between 27 February 2019 and 8 March 2019 in which participants, including those aged 20 and over, were asked to recall their intestinal symptoms before starting treatment.
to analyze the data using logical regression.
P less than 0.05 or less is considered a statistical difference.
the study included a total of 20,986 participants, according to the study.
Of these participants, 2,587 (1,036 men and 1,551 women, with an average age of 51.0 years) met the roman IV constipation criteria, but did not meet the IBS criteria and were therefore included in the CC group.
the same number of age/gender matching participants was randomly assigned to the non-CC control group, the RATE of LODD in the CC group was significantly higher than that in the non-CC group (57.4% vs 8.3%, P .lt;0.0 01;OR 14.84 (95% confidence interval 12.65-17.42)), the rate of LODD in CC individuals was higher than in patients in the non-CC control group of all age groups.
443 participants in the CC group were treated for constipation and were included in the CC-P group.
443 patients in the CC-P group, 285 (64.3%) had LODD before starting treatment, with a post-treatment LODD rate of 27.1% (120/443) and only 48.3% of CC-P patients said they were satisfied or somewhat satisfied with the treatment.
more than half are dissatisfied with their current treatment.
, the researchers concluded that LODDs were more common in CC patients than non-CC controls, and that treatment reduced the rate of LODD in CC patients.
, however, satisfaction with patients with persistent LODD is low, so improving LODD is critical to treatment satisfaction.
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