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    Home > Active Ingredient News > Digestive System Information > Clin Trans Gastroenterology: Intestinal selective broad-spectrum antibiotics have no effect on bacterial translocation and systemic inflammation of alcoholic hepatitis

    Clin Trans Gastroenterology: Intestinal selective broad-spectrum antibiotics have no effect on bacterial translocation and systemic inflammation of alcoholic hepatitis

    • Last Update: 2021-03-18
    • Source: Internet
    • Author: User
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    Although the medical community has conducted many clinical trials for Alcoholic Hepatitis (AH), the prognosis and treatment effect of Acute Alcoholic Hepatitis (AH) is still very poor, and basically unchanged for decades, which makes it appear to explore new treatment options.


    Although the medical community has conducted many clinical trials for Alcoholic Hepatitis (AH), the prognosis and treatment effect of Acute Alcoholic Hepatitis (AH) is still very poor, and basically unchanged for decades, which makes it appear to explore new treatment options.


     

     

    The researchers recruited 31 consecutive AH patients, and randomly gave 14 people to take vancomycin 500 mg, gentamicin 40 mg and meropenem 500 mg daily for 7 consecutive days.


     

     

    At the beginning of the study, the blood lipopolysaccharide binding protein level of all patients was many times higher than the normal level, which remained unchanged on the 7th day, but significantly decreased on the 90th day (P <0.


     

     

    This study confirms that in AH patients, antibiotic therapy targeting the intestine does not change bacterial translocation and markers of liver and systemic inflammation.


    This study confirms that in AH patients, antibiotic therapy targeting the intestine does not change bacterial translocation and markers of liver and systemic inflammation.


     

     

    Original source:

    Støy, Sidsel.


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    com/ctg/Fulltext/2021/02000/No_Effect_in_Alcoholic_Hepatitis_of_Gut_Selective,.
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    aspx" target="_blank" rel="noopener">No Effect in Alcoholic Hepatitis of Gut-Selective, Broad-Spectrum Antibiotics on Bacterial Translocation or Hepatic and Systemic Inflammation.
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