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Clin Trans Gastroenterology: Oral proton pump inhibitors may be as effective as intravenous injection in peptic ulcer bleeding

 Last Update: 2021-04-22
 Source: Internet
 Author: User

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Upper medsci.

The researchers searched all relevant randomized controlled trials in 4 databases and compared the results of oral PPI treatment with intravenous (IV) PPI treatment for PUB.

A total of 14 randomized controlled trials met the inclusion criteria, and a total of 1,951 patients with peptic ulcer were collected, of which 977 cases and 974 cases were in the control group and the intervention group, respectively.

Figure: Meta-analysis of the heterogeneity of various studies

This study confirms that oral PPI is not inferior to intravenous PPI treatment for patients with gastrointestinal bleeding after endoscopic treatment, but further research is necessary.

Original source:

Csiki, Endre.

lww.
com/ctg/Fulltext/2021/04000/Oral_Proton_Pump_Inhibitors_May_Be_as_Effective_as.
13.
aspx?context=LatestArticles" target="_blank" rel="noopener">Oral Proton Pump Inhibitors May Be as Effective as Intravenous in Peptic Ulcer Bleeding: A Systematic Review and Meta-analysis.
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