Clinical Infectious Disease: The effect of hypertension and the use of calcium channel blockers on the outcome of tuberculosis treatment

Tuberculosis (TB) is one of the leading causes of death worldwide.
About 1.
5 million people died of tuberculosis in 2018.
Nearly 90% of the cases were from developing countries.
At the same time, many low-income and middle-income countries The prevalence of hypertension has risen sharply, accounting for nearly 75% of global hypertension cases
.

This retrospective cohort study included all patients over 18 years of age who were treated for sensitive tuberculosis at National Taiwan University Hospital from 2000 to 2016, and then assessed the use of hypertension and CCB in the first 9 months of tuberculosis treatment, as well as Association of all-cause and infection- related mortality in patients with sputum smear microscopy and positive sputum culture at the second and sixth months
.

Among the 2894 patients, 1052 (36.
4%) had hypertension
.

This study found that within 9 months of starting tuberculosis treatment, all-cause mortality and infection-related mortality in hypertensive patients increased
.

Original source:

Vignesh Chidambaram.