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Non-alcoholic fatty liver disease (NAFLD) is one of the most common liver diseases in the world, with a global prevalence of approximately 25%
.
However, NAFLD is now considered a heart and metabolic disorders, all-cause mortality and cardiac vascular multisystem disease-related mortality
Non-alcoholic fatty liver disease (NAFLD) is one of the most common liver diseases in the world, with a global prevalence of approximately 25%
As we all know, we spend an average of one-third of our lives sleeping, and sleep plays a key role in cardiovascular health, endocrine and immune systems
.
However, in recent decades, the duration of sleep has decreased worldwide, and the prevalence of short sleep duration (defined as <6 hours) has exceeded 20%
immunity
Researchers used the Pittsburgh Sleep Quality Index to assess the sleep duration and quality of 143306 NAFLD-free Korean adults with an average age of 36.
6 years, and the average follow-up time was 4.
0 years
.
The degree of hepatic steatosis (HS) is assessed by the fibrosis 4 index (FIB-4) or NAFLD fibrosis score using ultrasound and liver fibrosis
A total of 27817 subjects in this study had HS, of which 1471 subjects had HS and intermediate/high FIB-4 scores
.
Researchers compared sleep durations of ≤5, 6, 8, and ≥9 hours with 7 hours and found that the rate of patients with HS was 1.
This study confirms that in young people, short sleep time is independently associated with increased risk of NAFLD events with or without medium/high fibrosis scores, indicating that insufficient sleep has a deleterious effect on the risk and severity of NAFLD
.
.
Original source:
Um, Yoo Jin.
Sleep Duration, Sleep Quality, and the Development of Nonalcoholic Fatty Liver Disease: A Cohort Study.
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