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    Home > Active Ingredient News > Digestive System Information > Clinical Translational Gastroenterology: The relationship between serum neurofilament light chain levels and mild hepatic encephalopathy in patients with liver cirrhosis

    Clinical Translational Gastroenterology: The relationship between serum neurofilament light chain levels and mild hepatic encephalopathy in patients with liver cirrhosis

    • Last Update: 2021-11-11
    • Source: Internet
    • Author: User
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    The so-called hepatic encephalopathy is what we commonly call hepatic coma.


    diagnosis

     

     Recent clinical studies have shown that hyperammonemia and inflammation may lead to neuronal cell death, while the onset of obvious hepatic encephalopathy (OHE) may lead to cognitive impairment.


     

    The researchers recruited 64 patients with liver cirrhosis (with or without MHE), as well as 68 age-matched stroke patients (n = 29), transient ischemic attack (n = 29), and healthy individuals ( n = 10) As a control, the patient's sNfL level was tested serologically


     

    Although it has long been generally believed that axon cell death in HE patients is rarely or even non-existent, and that HE is completely reversible, a clinical study by Bajaj et al.


    Although it has long been generally believed that axon cell death in HE patients is rarely or even non-existent, and that HE is completely reversible, a clinical study by Bajaj et al.


    Labenz, Christian.


    Association Between Serum Levels of Neurofilament Light Chains and Minimal Hepatic Encephalopathy in Patients With Liver Cirrhosis.


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