Colorectal cancer is drinking?

Only for medical professionals to read for reference.
Sugary drinks just make you fat? Young man, you are too naive, and the risk of colorectal cancer has soared twice.

Recently, the topic of "relying on milk tea for life" has swept the entire youth group in our country.

How obsessed are young people with milk tea? Some people say that half of the work enthusiasm of contemporary young people is supported by milk tea.

In order to close the distance between themselves and their fans, countless female stars have even rushed to market the "Milk Tea Girl" personality.

In addition, according to the "Life Consumption Report for the 2020 November Holiday" released by Meituan, a cup of milk tea from a local brand in Changsha is hard to find on its platform.
The order volume exceeded 1.
1 billion during the eleventh period, and the milk tea also directly introduced Changsha.
This is the top popular list of Internet celebrity cities.
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This is the power of milk tea! Figure 1: Today, have you "renewed your life"? In contrast, although "Happy Fertilizer Water" is not as popular as it is, it has never passed off as an "old generation Internet celebrity" that has been popular for decades, but has penetrated into the lives of young people in a low-key manner.
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Although the negative effects of milk tea and cola on human health are overwhelming, for example, milk tea is very likely to contain trans fatty acids, which will increase the risk of cardiovascular disease; while the phosphoric acid in cola can promote the loss of calcium in the bones.
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However, this time they were proposed for hanging, completely because they all contain sugar (to be precise, they contain fructose), and, compared with other types of sugar-sweetened beverages, milk tea and cola are the most popular among young people.
"Favoured" has a wider range of attacks.

This means that not only these two, but other sugary drinks also have similar safety hazards.
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Short-term happiness, overdraft is long-term health.
Recently, a study published in the international authoritative journal Gut It was found that there is a link between the consumption of sugar-sweetened beverages and the increased risk of colorectal cancer (CRC) in women under the age of 50.

Drinking a lot of sugar-sweetened beverages (13-18 years old) during adolescence and adulthood will increase the risk of CRC [1].

Figure 2: Study revealing the relationship between sugar-sweetened beverage intake and the risk of CRC To assess the relationship between the risk of early-onset CRC (CRC that occurs before the age of 50) and the frequency of intake of sugar-sweetened beverages, the study cited Data from the Nurses’ Health Study II (NHSII) also used a semi-quantitative food frequency questionnaire (covering 124 common foods from 1960 to 1982) on the diet of adolescents (in 1998, aged 13 to 18) An assessment was performed and all participants were followed up to 50 years of age, or death.

Remarks: 1.
The NHSII study started in 1989 and has not been terminated yet.

It included data from 116,429 female registered nurses between the ages of 25 and 42 in the United States.
The study participants conducted detailed reports on their life>
2.
In this study, 1 cup is equal to 8 ounces, which is approximately 236.
59 milliliters.

The study confirmed that in adults, women who drank more than 2 cups of sugar-sweetened beverages a day had an increased risk of early-onset CRC by 2.
2 times (RR 2.
18; 95% CI 1.
10-4.
35; compared with drinking less than 1 cup per week).
p=0.
02).
On this basis, for every extra cup of sugary beverage intake per day, the risk of early-onset CRC will continue to increase by 16% (RR 1.
16; 95% CI 1.
00-1.
36).

However, artificially sweetened beverages (ASB) are added every day in adulthood; such as beverages that replace fructose with artificial sweeteners such as xylitol, maltitol, aspartame, sucralose, and stevia.
These beverages are sometimes called “Sugar-free beverages”) or fruit juice intake has no significant association with the increased risk of early-onset CRC (ASB: RR 0.
93; 95% CI 0.
83-1.
04; fruit juice: RR 1.
20; 95% CI 0.
74-1.
94) (table 1).

Table 1: Association between the intake of sugary beverages in adulthood and the risk of early-onset CRC.
However, the editor here also reminds you not to take the risk of ASB lightly.
Some studies have shown that the intake of ASB can cause cardiovascular disease Increased mortality risk [2]. The study also found that after correcting for potential confounding factors in puberty, increasing the intake of 1 cup of sugar-sweetened beverages a day between the ages of 13 and 18 can increase the risk of subsequent early-onset CRC by 32% (RR, 1.
32; 95%CI 1.
00-1.
75).

Table 2: The association between the intake of sugar-sweetened beverages and the risk of early-onset CRC in the 13-18 age group.
Finally, the study also discussed that the per capita consumption of beverages in the United States has risen sharply (an increase of approximately 500%).
In the second half of the 20th century.

Compared with the older generation, people born in this period are younger/younger when they drink sugary drinks for the first time and consume higher amounts.

The birth cohort during this period coincided with the overall increase in the incidence of early-onset CRC in the United States.
On the other hand, it confirmed the connection between sugar-sweetened beverages and the risk of early-onset CRC.

So, is there a drink that can reduce the risk of early-onset CRC? The study also concluded that the use of skimmed or whole milk instead of sugar-sweetened beverages is particularly beneficial in reducing the risk of early-onset CRC.
Milk and calcium may have a protective effect on the occurrence of early-onset CRC.

From 1989 to 2008, while the consumption of sugar-sweetened beverages by American school-age children increased by 63%, milk consumption also decreased by 22%.
The reduction in milk intake is likely to further aggravate early-onset CRC in young people.
risk.

Why can sugar cause CRC? Various biological mechanisms support the existence of this correlation.

Compared with the intake of other caloric solid foods, sugary drinks lacking dietary fiber can inhibit satiety, promote excessive energy intake, and ultimately lead to weight gain.

In addition, sugar-sweetened beverages have a high glycemic index (GI) due to the addition of a large amount of fructose, which can quickly trigger an increase in blood sugar and insulin secretion in a short period of time.
In the long run, the body is prone to insulin resistance, inflammation, obesity and type 2 diabetes.
These metabolic factors are all related to the increased risk of CRC.

In addition, excess fructose exceeding the absorption capacity of the small intestine reaches the colon, which can also cause dysbiosis and endotoxemia, damage the intestinal barrier function, increase intestinal permeability, and promote the occurrence of CRC.

A recent study showed that mice treated with high fructose corn syrup had a large number of colon tumor growth, and the tumor was aggressive.
This change was independent of obesity and metabolic syndrome, which was the difference between sugary drinks and the risk of CRC.
Contact provided additional support.

After reading it at the end, I believe you must have a certain understanding of the dangers of sugary drinks.

Now, do you choose to move your fingers and forward the article to the "family in love" group, or do you have a cup of milk tea to be shocked? References: [1]Jinhee Hur,Ebunoluwa Otegbeye,Hee-Kyung Joh.
et al.
Sugar-sweetened beverage intake in adulthood and adolescence and risk of early-onset colorectal cancer among women.
Gut 2021 May 06.
[2]Qin P ,Li Q,Zhao Y,et al.
Sugar and artificially sweetened beverages and risk of obesity,type 2 diabetes mellitus,hypertension,and all-cause mortality:a dose-response meta-analysis of prospective cohort studies.
Eur J Epidemiol 2020 Jul ;35(7).