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Herpes Simplex Virus (HSV) is a neurotropic double-stranded DNA enveloped virus that lives in large numbers in nature and can invade humans and animals to cause infection .
The virus usually infects the body through mucous membranes, skin, and nervous tissues.
Lesions
.
The seroprevalence of HSV-1 and HSV-2 in the population is 68% and 22%, respectively
.
HSV-1 is one of the most widespread viral infections in the world.
Herpes Simplex Virus (HSV) is a neurotropic double-stranded DNA enveloped virus that lives in large numbers in nature and can invade humans and animals to cause infection .
The virus usually infects the body through mucous membranes, skin, and nervous tissues.
Lesions
.
1.
Biological characteristics
Biological characteristics 1.
Biological characteristics
HSV is a circular virus composed of envelope, capsid, core, and envelope.
The double-stranded linear DNA structure filaments are wound in coils
.
The genome length of HSV-1 is 125~240kb, and the genome length of HSV-2 is about 154kb
Immunization prevention
2.
Infection characteristics
Infection characteristics 2.
Infection characteristics encephalitis trigeminal nerve
3.
Clinical manifestations
Clinical manifestations 3.
Clinical manifestations in children
4.
Principles of treatment
Principles of treatment 4.
Principles of treatment
Relieve the psychological burden of patients, reduce the recurrence rate and relieve symptoms Therapy involves health education, antiviral, immune and local treatments
.
At present, the main treatment method is systemic antiviral, famciclovir, valacyclovir and acyclovir are commonly used drugs
5.
Current status of virus vaccine research
Current status of viral vaccine research 5.
Current status of viral vaccine research
Vaccination is still an ideal way to prevent viral infections
.
The vaccinated vaccine can fully exert the immune effect of HSV-2 against infection, mobilize the functions of humoral and cellular immunity in the body, and eliminate HSV infection in the body
6.
Detection method
Detection method 6.
Detection method
(1) Antibody test: HSV antibody test (IgM) is still the most commonly used clinical method to detect HSV infection
.
After being infected with HSV for the first time, anti-HSV antibodies will reach a peak in about 5 weeks and remain stable, and the IgM antibodies of HSV produced at the initial stage can be maintained for about 7 weeks
(2) PCR detection: The sensitivity of viral nucleic acid detection is higher than that of cell culture, and it has initially shown greater superiority in clinical virus testing
.
Sample type: female cervical secretion/male urethral secretion
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